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. 2018 May 15;10:139. doi: 10.3389/fnagi.2018.00139

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Copyright © 2018 Shah, Zhao, Hussain, Sabir and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The schematic presentation of autophagy pathway and core autophagy-related proteins targeted by various miRNAs. The figure shows some significant miRNAs (dark green color) and their respective targets (light green and yellow color) for the regulation of autophagic mechanisms in Alzheimer’s and Parkinson’s disease. The figure shows that insufficient research has been conducted in neurodegenerative diseases for the regulation of autophagy via miRNAs and further molecular research is encouraged in all major neurodegenerative diseases including prion diseases.