Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 15;9:912. doi: 10.3389/fmicb.2018.00912

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Pachón-Ibáñez, Labrador-Herrera, Cebrero-Cangueiro, Díaz, Smani, del Palacio, Rodríguez-Baño, Pascual, Pachón and Conejo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Time-kill curves for colistin (CST) and rifampin (RIF) alone and in combination against four clinical strains of carbapenemase producing strains (VIM-1, VIM-1/DHA-1, OXA-48/CTX-M-15 and KPC3). The CST concentration used for colistin-susceptible strains corresponded to the value of their MICs (colistin 0.5 mg/L for VIM-1 and OXA-48/CTX-M-15); for colistin-resistant isolates the concentration of CST was that corresponding to the susceptibility breakpoint recommended by EUCAST (colistin 2 mg/L for VIM-1/DHA-1 and KPC-3). The RIF concentration used for all strains was 2 mg/L. RIF, filled circles; CST, filled squares; combination of both antimicrobials, filled triangles.