Figure 1.

Force-mediating nanoparticles and their interplay with mammalian cell function. (A) FMNPs as mediators to direct cell guidance through the extracellular space when exposed to a permanent magnetic field gradient (t: time). (B) FMNPs associated to the cell membrane can control receptor functionality, stimulate cell communication, or perform local cell surgeries. (C) Positioning of fMNPs inside cells can establish protein gradients and modulate vesicle dynamics. (D) Localizing FMNPs to the cell nucleus is utilized to genetically modify cells, here demonstrated through the translation of a fluorescent protein (e.g., GFP, or eGFP).