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. 2018 May 15;12:299. doi: 10.3389/fnins.2018.00299

Figure 4.

Figure 4

Controlling calcium influx with alternating (AMF) and permanent magnetic fields (PMF). (A) Heat stimulation of TRPV1 through fMNP-mediated heat induction in AMF. (B) FMNP-mediated calcium channel activation via membrane bending in PMF. “B = 0” indicates no magnetic field. (C) False color heat maps show changes in fluorescently-labeled intracellular calcium concentration in TRPV1- and TRPV+ HEK293FT cells before and during AMF stimulation. Scale bar = 50 μm. Reproduce with permission from Chen et al. (2015), Copyright © 2015, American Association for the Advancement of Science. (D) False color heat maps show changes in fluorescently-labeled intracellular calcium influx in primary cortical neurons (E18, rat) with and without fMNPs and with and without PMF stimulation. Reproduce with permission from Tay et al. (2016a), Copyright © 2016, American Chemical Society.