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. 2018 May 15;9:529. doi: 10.3389/fphys.2018.00529

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Copyright © 2018 Wang, Wang, Chen, Zhao and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Xinnao shutong attenuates numbers of microglia in hippocampal CA1 and dentate gyrus following chronic cerebral hypoperfusion. (A) Representative immunofluorescence images showing Iba1-positive (microglial marker) cells in cortex, hippocampal CA1, CA3, dentate gyrus, and corpus callosum 42 days following BCCA ligation. Scale bar = 50 μm. (B) Quantitative analysis of Iba1⁺ cells in different regions. (C) Western blot detection and quantitative analysis of Iba1. Values are expressed as mean ± SEM (n = 12). ^∗p < 0.05 vs. Sham, ^∗∗p < 0.01 vs. Sham, ^#p < 0.05 vs. Model.