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. 2018 May 15;9:958. doi: 10.3389/fmicb.2018.00958

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Copyright © 2018 Fernández-Cabezón, Galán and García.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Microbial functionalization of steroidal molecules of industrial relevance. (A) Δ1-Dehydrogenation of 3-ketosteroids: conversion of cortisone into prednisone. (B) 9α-Hydroxylation of 3-ketosteroids: conversion of progesterone into 9α-hydroxy-progesterone. (C) 11α-Hydroxylation of 3-ketosteroids: conversion de AD into 11α-hydroxy-AD. (D) Baeyer-Villiger oxidation: conversion of ADD into testolactone. KstD, 3-ketosteroid-Δ¹-dehydrogenase, KSH, 3-ketosteroid-9α-hydroxylase, P450, 11α-hydroxylase, cytochrome P450, BMVO, Baeyer-Villiger monooxygenase.