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. 2018 May 15;9:536. doi: 10.3389/fphys.2018.00536

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Copyright © 2018 Chen, Sun, Chen, Gu, Zhang, Yang, Peng, Dong and Lai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of microinjection into the DVC on airway microvascular leakage in a guinea pig model of HCl perfusion. Airway inflammation was aggravated by microinjection of exogenous SP and Glu into the DVC but was alleviated by anti-SP serum, GABA, and lidocaine. (A) Airway microvascular leakage was observed via EBD (white arrow) after drug microinjection into the DVC. EBD mean densities and concentrations in six groups are presented in (B,C). Data are expressed as the mean ± SD. ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001 vs ACSF group; one-way ANOVA followed by LSD test.