Table 5.

Platelet function analysis.

rs12566888	hc of major allele median	minor allele carriers median	Difference in location	Lower/upper 95% CI	WMW test p-value	Median regression p-value*
Mean platelet volume	9.8	5.9	0.2	−0.6, 1	0.6	0.31
Platelet count	238	226	8	−6, 23	0.28	0.083
Platelet aggregation test:
ADP	34	24	4	0, 9	0.065	0.13
Arachidonic acid	13	12	1	−1, 3	0.33	0.43
TRAP test	82	79	5	−1, 11	0.09	0.15
Collagen test	36	33	4	−5, 15	0.37	0.88
rs2768759	major allele carriers median	hc of minor allele median	Difference in location	Lower/upper 95% CI	WMW test p-value	Median regression p-value*
Mean platelet volume	8.90	9.60	0.2	−0.9, 0.9	0.68	0.056
Platelet count	236	240	0	−26, 26	0.98	0.89
Platelet aggregation test:
ADP	32	24	4	−3, 12	0.25	0.21
Arachidonic acid	13	11.50	2	−1, 5	0.12	0.63
TRAP test	82	75.5	3	−6, 12	0.49	0.14
Collagen test	37	33	6	−6, 24	0.32	0.35
rs41273215	hc of major allele median	minor allele carriers median	Difference in location	Lower/upper 95% CI	WMW test p-value	Median regression p-value*
Mean platelet volume	9.90	9.55	0.3	−0.2, 0.8	0.18	0.12
Platelet count	243	218	14	1, 27	0.028	0.036
Platelet aggregation test:
ADP	33	26	4	−1, 8	0.1	0.13
Arachidonic acid	13	13	1	−1, 2	0.45	0.3
TRAP test	83	75	7	2, 12	0.0094	0.0042
Collagen test	37	30	7	−2, 18	0.13	0.73

^*With covariates P2Y₁₂ antagonist, reason for admission (stable CAD/type of ACS), arterial hypertension, hyperlipidemia, smoking, diabetes mellitus, medication (ASA, ACE inhibitors, beta blockers, statins), age, gender, and LVEF.

WMW, Wilcoxon-Mann-Whitney.