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. 2018 May 15;9:527. doi: 10.3389/fphys.2018.00527

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Copyright © 2018 Li, Li, Pan, Yan, Hu, Liu, Yang, Huang, Zhao, Wang, Fan, Wang and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of BSHX on the number of open microvessels in mouse hippocampus. (A) Representative immunohistochemistry images of mouse hippocampus region in different groups. Arrows represent open microvessels. a1: C57 group; a2: KKAy group; a3: KKAy + BSHX 1 g/kg group; a4: KKAy + BSHX 2 g/kg. Bar = 200 μm. High magnifications of a1–a4 are shown below as b1–b4, respectively. Bar = 50 μm. (B) Quantitative analysis of CD-31 positive opening microvessels. Data were expressed as mean ± SD (n = 5). ^*p < 0.05 vs. C57 group, ^#p < 0.05 vs. KKAy group.