Table 1.
Information of pre- and post-splenectomy patients compared with health control.
| LC | |||||
|---|---|---|---|---|---|
| Pre | Post | Control | |||
| n = 12 | n = 12 | p-value | n = 16 | p-value | |
| Age | 45.4 ± 9.7 | 47.0 ± 8.5 | 0.72 | ||
| Male/female | 7/5 | 9/7 | >0.99 | ||
| BMI (kg/m2) | 23.2 ± 0.8 | 23.3 ± 0.9 | 0.88 | 23.1 ± 1.0 | 0.75 |
| Total bilirubin (μmol/L) | 31.1 ± 27.5 | 17.9 ± 8.3 | 0.09 | 11.1 ± 4.3 | |
| Albumin (g/L) | 39.4 ± 5.7 | 42.7 ± 3.5 | 0.02 | 42.3 ± 3.4 | |
| Prothrombin time (s) | 13.8 ± 1.1 | 12.0 ± 0.6 | <0.01 | 12.2 ± 0.5 | |
| Prothrombin activity | 57.4 ± 15.0 | 79.0 ± 8.6 | <0.01 | 76.0 ± 8.8 | |
| ALT (U/L) | 52.7 ± 75.0 | 36.6 ± 14.2 | 0.49 | 15.3 ± 10.3 | |
| AST (U/L) | 77.7 ± 126.1 | 47.1 ± 17.5 | 0.43 | 19.3 ± 6.2 | |
| Total bile acids (μmol/L) | 42.1 ± 25.7 | 20.2 ± 10.4 | <0.01 | 5.1 ± 3.1 | |
| White blood cell count (109/L) | 2.0 ± 0.5 | 5.2 ± 1.0 | <0.01 | 6.5 ± 2.6 | |
| Platelet count (109/L) | 44.2 ± 17.6 | 340.5 ± 154.4 | <0.01 | 266.1 ± 43.2 | |
| Ascites | 5(42) | 1(8) | |||
| Encephalopathy | 0(0) | 0(0) | |||
| Child–Pugh score (points) | 6.2 ± 0.9 | 5.1 ± 0.3 | <0.01 | ||
| Child–Pugh class (A/B/C) | 8/4/0 | 12/0/0 | |||
Student’s t-test was used to compare age and BMI between LC (n = 12) and control (n = 16). Fisher’s exact test was used to compare gender distribution between LC and control. Paired Student’s t-test was used to compare clinical indices of LC before and after splenectomy. Values are expressed as the means ± SD. Numbers in parenthesis are %. ALT, alanine transaminase, AST, aspartate aminotransferase, BMI, body mass index.