NF-ĸB/p65 staining scores analysis. Median staining score evaluation among normal adjacent mucosa, tumor tissue and non CRC tissue (X2(1)=39.146, P<0.001). Pairwise comparison among groups is also shown (tumor tissue vs. normal adjacent mucosa, z=−5.707, P<0.001), (tumor tissue vs. non-CRC tissue (z=−4.126, P<0.001). NF-κB, nuclear factor-κB.