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. 2018 Mar 23;15(5):8027–8033. doi: 10.3892/ol.2018.8329

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Figure 1. — Immunohistochemical examination of human gastric cancer tissues for Tie2 and CAIX. (A) Gastric cancer tissue with positive Tie2 expression. Tie2 was primarily expressed in the gastric cancer cells. Tie2 is mainly expressed in the cytoplasm of macrophages, and the cytoplasm is stained brown and yellow. (B) CAIX positive expression in gastric cancer tissue. CAIX is mainly expressed in the cytoplasm of gastric cancer cells, and the cytoplasm is stained brown and yellow. (C) Numerous Tie2-expressing macrophages were located in the tumor stroma (marked with red arrows). (D) Gastric cancer tissue that is negative for Tie2 expression. Magnification, ×400. Tie2, Tunica Interna endothelial cell kinase; CAIX, carbonic anhydrase IX.