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Immunostimulatory activity of RIG-I-associated RNA. (a) RIG-I-associated RNA from SeVΔC-infected A549 cells or control IP RNA was transfected into 293T ISRE-Fluc cells. Data from three individual experiments with SD are shown. (b) ISRE-Fluc reporter activation by RIG-I IP RNA or poly(I:C) treated with calf alkaline phosphatase (CI) and RNAse A.
