Table 1.
World Health Organization criteria* for diagnosis of definite acute MI, possible acute MI or old MI
| Type of evidence | Criteria |
| History | The history is typical if severe, prolonged chest pain is present. Sometimes the history is atypical, and the pain may |
| be mild or even absent, or other symptoms may be predominant | |
| Electrocardiography (ECG) | Unequivocal changes in ECG are the development of abnormal, persistent Q or QS waves, and evolving injury |
| current lasting longer than 1 day. When the ECG shows these unequivocal changes, the diagnosis may be made | |
| on the basis of ECG alone. In other cases the ECG may show equivocal changes, consisting of a stationary injury | |
| current, a symmetrical inversion of the T-wave, a pathological Q-wave in a single ECG record, or conduction | |
| disturbances | |
| Serum enzymes | Unequivocal changes consist of serial change, or initial rise and subsequent fall of the serum level. The change |
| must be properly related to the particular enzyme, and to the delay time between onset of symptoms and blood | |
| sampling. Elevation in cardio-specific isoenzymes is also considered unequivocal change. Equivocal change | |
| consists of an enzyme pattern in which an initially elevated level is not accompanied by a subsequent fall - the | |
| curve of enzyme activity is not obtained |
*Revised 1994 for the MONICA study [1].