Table 2.

Phenelzine 12 h Intermittent Dosing Paradigm

Group	Loading Dose (15 min post-injury)	Maintenance dosing: 12 h, 24 h, 36 h, 48 h, 60 h
Sham	None	None
Vehicle	Saline s.c.	Saline s.c.
Phenelzine	10 mg/kg s.c. PZ	5 mg/kg s.c. PZ

Demonstration of the PZ 12 h intermittent dosing paradigm followed. Loading doses were administered 15 min following impact. Maintenance doses were administered every 12 h up to and including 60 h. Animals were euthanized 72 h post-injury. Saline was prepared to deliver an equal amount of saline as PZ animals.

PZ, phenelzine (in saline); s.c., subcutaneous.