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. 2018 May 22;90(21):e1889–e1897. doi: 10.1212/WNL.0000000000005550

Figure 1. ADAS-Cog12 scores.

Figure 1

Mean change from baseline to week 73 in (A and D) mild to moderate (MMSE score 18–26), (B and E) mild (MMSE score 20–26), and (C and F) milder (MMSE score 22–26) populations. (A–C) Low-dose 300 mg SC cohort. (D–F) High-dose 15 mg/kg IV cohort. Error bars show SE of the least-squares mean. AD = Alzheimer disease; ADAS-Cog12 = 12-point Alzheimer's Disease Assessment Scale–Cognitive Subscale; BL = baseline; Cr = crenezumab; Diff = difference; MMSE = Mini-Mental State Examination; %Red = percentage reduction; Pl = placebo; SC = subcutaneous; SE = standard error.