Postinfection administration of MAb to PNAG reduces conjunctival myeloperoxidase due to S. pneumoniae (D-39 and ATCC8) and S. aureus (LAC) after 48 hours of conjunctival infection in A/J mice. A total of 10 μg of control IgG MAb (□) or MAb to PNAG (▵) were injected into the conjunctiva 4, 24, and 32 hours postinfection with S. pneumoniae (D-39, ATCC8) or S. aureus LAC. Mice were euthanized at 48 hours postinfection and MPO/conjunctiva was determined. Symbols represent individual animals, black lines the medians, and gray lines the 95% CI, and P values were determined by one-sided nonparametric t-tests.