Table 3. Percentage of Approved Prescriptions Dispensed and Factors Associated WIth Dispensing After Approval Among Approved Prescriptions.
| Subgroup | No. Approved | Dispensed After Approval, No. (%) |
Multivariable Results for Dispensing After Approval, OR (95% CI) |
|---|---|---|---|
| Overall | 21 259 | 13 891 (65.3) | NA |
| Age, y | |||
| <45 | 469 | 367 (78.2) | 1 [Reference] |
| 45-54 | 1736 | 1422 (81.9) | 1.06 (0.76-1.47) |
| 55-64 | 4441 | 3414 (76.9) | 1.02 (0.75-1.39) |
| 65-74 | 9435 | 5687 (60.3) | 1.11 (0.82-1.50) |
| >75 | 5178 | 3001 (58.0) | 1.02 (0.75-1.39) |
| Sex | |||
| Male | 10 905 | 6940 (67.0) | 1 [Reference] |
| Female | 10 354 | 6951 (63.7) | 0.83 (0.77-0.89) |
| Pharmacy | |||
| Retail | 14 882 | 9982 (67.1) | 1 [Reference] |
| Institutional | 102 | 74 (72.6) | 1.41 (0.81-2.47) |
| Mail order | 218 | 159 (72.9) | 3.44 (1.82-6.49) |
| Specialty | 6057 | 3676 (60.7) | 0.89 (0.82-0.97) |
| Clinician type | |||
| General practice | 6740 | 4261 (63.2) | 1 [Reference] |
| Cardiology | 11 485 | 7539 (65.6) | 1.18 (1.08-1.29) |
| Endocrinology | 997 | 660 (66.2) | 1.06 (0.87-1.28) |
| Other | 2037 | 1431 (70.2) | 1.49 (1.29-1.72) |
| Payor type | |||
| Commercial only | 5111 | 4071 (79.7) | 1 [Reference] |
| Government only | 14 236 | 8418 (59.1) | 0.57 (0.50-0.64) |
| Commercial and government | 1084 | 762 (70.3) | 0.68 (0.55-0.83) |
| Other | 828 | 640 (77.3) | 1.17 (0.91-1.51) |
| Copay, $ | NAa | NAa | 1 [Reference] |
| 10 | NAa | NAa | 0.81 (0.81-0.82) |
| 20 | NAa | NAa | 0.66 (0.65-0.67) |
| 40 | NAa | NAa | 0.44 (0.43-0.45) |
| 100 | NAa | NAa | 0.16 (0.15-0.17) |
| 200 | NAa | NAa | 0.06 (0.05-0.06) |
| 300 | NAa | NAa | 0.04 (0.03-0.04) |
| 500 | NAa | NAa | 0.03 (0.03-0.03) |
| Time to approval, d | |||
| 0-1 | 9858 | 6620 (67.2) | 1 [Reference] |
| 2-7 | 2829 | 1908 (67.4) | 1.06 (0.94-1.19) |
| 8-14 | 2263 | 1432 (63.3) | 0.90 (0.79-1.03) |
| 15-31 | 2647 | 1602 (60.5) | 0.74 (0.65-0.83) |
| >1 mo | 3662 | 2329 (63.6) | 0.78 (0.70-0.87) |
Abbreviations: NA, not applicable; OR, odds ratio.
a
Multivariable model results from copay reflects ultimate out of-pocket costs after co-insurance, patient approval program use, and coupon use. Because copay was modeled using restricted cubic splines, representative ORs are presented at each copay level. See Figure 2 for absolute dispense rates by copay ranges.