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. 2018 May 21;11:319. doi: 10.1186/s13104-018-3446-y

Table 2.

Assessment of in vitro drug interactions against L. major (5ASKH strain) promastigotes

Serial no. Drug combination Mean FICsa Nature of the interaction
1 Paromomycin–suramin 0.41 ± 0.05 Synergism
2 Netilmicin–suramin 0.69 ± 0.29 Indifference
3 Primaquine–suramin 0.90 ± 0.08 Indifference
4 Primaquine–netilmicin 1.14 ± 0.2 Indifference
5 Primaquine–paromomycin 1.68 ± 0.15 Indifference
6 Paromomycin–netilmicin 2.6 ± 0.4 Indifference

Results are given as mean ± SD of three independent experiments

aMean of FICs were used to define the nature of the interactions between the drugs against L. major (5ASKH strain) promastigotes