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. 2018 May 22;12:136. doi: 10.1186/s13256-018-1671-6

Fig. 5.

Fig. 5

The resected lung specimen resembled the previous distal cholangiocarcinoma. Histopathological examination (H&E staining) of the lung tumor showed tumor cells forming irregular tubular structures with a lepidic pattern (a, original magnification × 10; b, original magnification × 200). Immunohistochemically, the tumor cells were positive for cytokeratin 7 (c, original magnification × 200) and CDX-2 (d, original magnification × 200) and negative for thyroid transcription factor 1 (e, original magnification × 200), napsin A (f, original magnification × 200), and cytokeratin 20 (g, original magnification × 200)