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. 2018 May 21;16:22. doi: 10.1186/s12964-018-0234-1

Fig. 6.

Fig. 6

The effects of downregulation and upregulation of AnnexinA7 on the expressions of SDF1/CXCR4 in hepatocarcinoma cells in vitro and in vivo. Cytoimmunofluorescence (cell nuclear DAPI staining A1, B1; cell staining A2, B2; merged picture, A, B) and immunohistochemistry (C, D) analysis of SDF1/CXCR4 expressions in FSHUS, FA7DOWN (left), PNCEV and PA7UP (Right) cells in vitro (A1,A2, B1,B2,A, B) and in vivo (C, D). SDF1 expressions in FSHUS and FA7DOWN cells in vitro (A1, A2, A, Left). SDF1 expressions in PNCEV and PA7UP cells in vitro (A1, A2, A, Right). CXCR4 expressions in FSHUS and FA7DOWN cells in vitro (B1, B2, B, Left). CXCR4 expressions in PNCE and PA7UP cells in vitro (B1, B2, B, Right). SDF1 expressions in FSHUS and FA7DOWN cells in vivo (C, Left). SDF1 expressions in PNCEV and PA7UP cells in vivo (C, Right). CXCR4 expressions in FSHUS and FA7DOWN cells in vivo (D, Left). CXCR4 expressions in PNCEV and PA7UP cells in vivo (D, Right). Cytoimmunofluorescence and immunohistochemistry results (OD) for SDF1/CXCR4 in FSHUS, FA7DOWN, PNCEV and PA7UP cells in vitro (E)and in vivo (F); * indicates that P < 0.05 as statistically significant