Table 2.
Association of SDF-1 levels, CXCR4+ cells and mRNA expression of CXCR4 and CXCR7 receptors in the BM
| Study variables | IHD | VHD |
|---|---|---|
| r/P/n | r/P/n | |
| SDF-1 vs. CXCR4+ cells | − 0.10/0.87/5 | 1.00*/< 0.05/4 |
| SDF-1 vs. CXCR4 mRNA | 0.60/0.20/6 | − 0.21/0.62/7 |
| SDF-1 vs. CXCR7 mRNA | − 0.71/0.11/6 | 0.64/0.11/7 |
| CXCR4+ cells vs. CXCR4 mRNA | − 0.70/0.18/5 | 0.80/0.20/4 |
| CXCR4+ cells vs. CXCR7 mRNA | 0.00/1.00/5 | 0.40/0.60/7 |
| CXCR4+ mRNA vs. CXCR7 mRNA | − 0.42/0.39/6 | − 0.21/0.64/7 |
Stromal-derived-factor-1 (SDF-1, pg/mL); CXCR4+ populations (% CD184+ cells); CXCR4 and CXCR7 mRNA expressed in log10 of the relative expression
r Spearman’s correlation coefficient, P significance level, n sample, IHD ischemic heart disease, VHD valvular heart disease
* Strong direct correlation (P ≤ 0.05)