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Effect of monepantel on acetylcholine EC50 and Rmax values for Ode levamisole receptors.
| EC50 (mean ± s.e.m., n) | Rmax (mean ± s.e.m., n) | |
|---|---|---|
| Acetylcholine | 2.7 ± 0.4 μM, n = 4 | 108.8 ± 1.0%, n = 4 |
| +1 μM monepantel | 3.8 ± 0.4 μM, n = 4 | 87.9 ± 1.2%, n = 4 |
| +3 μM monepantel | 2.7 ± 0.4 μM, n = 4 | 69.3 ± 3.2%, n = 4 |
| +10 μM monepantel | 2.2 ± 0.4 μM, n = 4 | 25.0 ± 1.4%, n = 4 |
| +30 μM monepantel | 1.8 ± 0.3 μM, n = 5 | 3.9 ± 0.1%, n = 5 |
