Table 2.

Variants in genes known to be involved in Parkinson’s disease (PD) pathogenesis.

Gene	dbSNP141 RS ID	Amino acid change	MAF (EXAC)	REVEL score	CADD score	Association with PD	Reference
GBA	rs2230288	NM_001171811 E365K	0.0098	0.595	17.33	Risk factor	Benitez et al. (2016)
GBA	rs75548401	NM_001171811 T408M	0.0066	0.731	22.2	Risk factor	Benitez et al. (2016)
LRRK2	rs34594498	A419V	0.0005	0.175	24.3	Risk factor	Ross et al. (2011) and
							Li et al. (2015)

Note: MAF, minor allele frequency.