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. 2018 May 21;15:89. doi: 10.1186/s12985-018-1002-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The doses of plasmid backbone are critical for HBV persistence. WT mice were hydrodynamically injected with 6 μg pAAV/HBV1.2, 6 μg pAAV/HBV1.2 plus 14 μg pAAV/control, and 20 μg pAAV/HBV1.2 respectively. Serum levels of HBsAg (a) and positive rate of serum HBsAg (b) were shown at indicated time points