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. 2018 May 21;37:107. doi: 10.1186/s13046-018-0772-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Co-treatment of olaparib and doxorubicin inhibited growth of KHOS/NP osteosarcoma cells in mice. a The gross and histologic findings of KHOS/NP osteosarcoma around the knee of mice. The tumor volume (b) and tumor weight (c) were significantly decreased with treatment of 10 μM olaparib or 0.2 μM doxorubicin. Especially, tumor growth was significantly decreased with co-treatment of 10 μM olaparib and 0.2 μM doxorubicin in mice. *, P < 0.05; **, P < 0.001