Table 2.

Functional gene categories showing significant enrichment for CNVs

Functional gene set	No. of genes in CNVs	Total no. of genes in gene set	Nominal	Adjusted
			P-valuea	P-valueb
Deletions
Exported proteins - PHISTs	8	48	< 0.001	< 0.001
Characteristics of Plasmodium falciparum export proteins that remodel infected erythrocyte	5	35	< 0.001	0.043
Glycolysis	4	27	0.001	0.10
Exported proteins - Unique	6	72	0.0025	0.10
Utilization of phospholipids	4	40	0.005	0.26
Amplifications
Rab and other proteins involved in intracellular traffic	3	14	0.009	1
RNA binding genes	12	173	0.01	1

^aBy hypergeometric test without adjustment for testing of multiple gene sets

^bAdjusted for multiple-testing by the Benjamini-Hochberg method