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. 2016 Jun 13;8(1):41–52. doi: 10.1080/21505594.2016.1200215

Figure 4.

Figure 4.

Model of miR155 activation in BMDMs exposed to C. albicans hyphae. miR155 activation by C. albicans. Exposure of β-glucans in the fungal cell wall interact with Dectin 1, inducing a Syk-dependent pathway that results in the upregulation of mature miR155. Activation of either TLR 2 or 4 inhibits the accumulation of the mature miRNA.