Table 1.
miRNA\Condition | Yeast 8hrs | Hypha 8hrs | Yeast 16hrs | Hypha 16hrs |
---|---|---|---|---|
miR125b | 1.19 ± 0.21 | 2.44 ± 0.05* | 2.62 ± 1.43 | 2.75 ± 0.52* |
miR132 | 1.51 ± 0,73 | 5.16 ± 1.25** | 1.36 ± 0.10 | 6.37 ± 0.03** |
miR146a | 3.33 ± 1.20* | 8.10 ± 0.72** | 2.08 ± 0.17* | 3.79 ± 0.95* |
miR155 | 4.65 ± 1.95 | 6.37 ± 4.33 | 0.79 ± 0.12 | 1.50 ± 0.02 |
miR455 | 0.82 ± 0.32 | 2.86 ± 0.09* | 0.86 ± 0.34 | 1.98 ± 1.04 |
miR9 | 2.54 ± 0.10* | 5.61 ± 0.80*** | 1.22 ± 0.13 | 1.52 ± 0.26 |
miR199 | 7.51 ± 5.14 | 32.50 ± 5.26** | 1.19 ± 0.31 | 2.59 ± 0.72 |
miR221 | 3.44 ± 1.85 | 4.04 ± 0.40** | 0.71 ± 0.06 | 2.72 ± 1.64 |
miR223 | 3.62 ± 1.96 | 5.67 ± 0.16** | 2.07 ± 0.2 | 2.35 ± 0.56 |
Note. Interaction assay of BALB/c BMDMs and heat-killed yeasts or hyphae of C. albicans, employing a MOI of 2 for 8 or 16 hours. Levels of expression were measured by qRT-PCR. Fold change of expression is represented by the mean of 3 independent pooled experiments ± SEM. Statistical analyses were performed by Two-way ANOVA and Tukey's post-test. Bold numbers represent differentially expressed values (p-value < 0.05), whereas asterisks indicate p-value;
(
)
p < 0.05,
(
)
p < 0.01,
(
)
p < 0.001,
(
)
p < 0.0001.