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. 2018 May 14;10:134. doi: 10.3389/fnagi.2018.00134

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At least a portion of this work is authored by Neel K. Sharma, Rupali Sharma, Shashwat Sharad and Sanchita P. Ghosh on behalf of the U.S. Government and, as regards Drs. Sharma, Sharma, Sharad, Ghosh and the US government, is not subject to copyright protection in the United States. Foreign and other copyrights may apply.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Low dose Ionizing radiation confer not only the neuroprotection but also activate reparative mechanisms. (A) Neuroinflammation may decrease by low dose ionizing radiation and can lead in increased antioxidants and reduced oxidative stress. (B) Neuroinflammation can be provoked by high dose ionizing radiation lead to microglia activation and ROS which can affect the cell functioning. Reproduced with permission (Betlazar et al., 2016).