Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A generic two-stage sequential multiple assignment randomized trial (SMART) design where participants are randomized between any number of treatments A1 to AJ. Response is measured at some intermediate time point or over time such that responders are re-randomized in the second stage between any number of treatments B1 to BK and non-responders are re-randomized between any number of treatments C1 to CL. The same participants are followed throughout the trial.
