Table 2.
Suprathreshold voxel clusters, p < 0.05 FDR corrected | Puncorr (cluster) | |||||||
---|---|---|---|---|---|---|---|---|
| ||||||||
Cluster no. | Coordinates (Talairach)
|
Cluster size KE | Location (nearest gray matter) | T | qFDR Corr (peak) | |||
X | Y | Z | ||||||
1 | −2 | −58 | 32 | 3011 | Left precuneus | 5.59 | 0.022 | 0.000 |
2 | 18 | −52 | −13 | 103 | Right cerebellar culmen | 5.16 | 0.022 | 0.274 |
3 | −57 | −40 | 17 | 902 | Left superior temporal gyrus | 5.12 | 0.022 | 0.004 |
4 | −38 | −44 | −19 | 252 | Left cerebellar culmen | 5.12 | 0.022 | 0.095 |
5 | −38 | 4 | 1 | 350 | Left insula | 4.99 | 0.022 | 0.054 |
6 | −29 | −38 | −7 | 633 | Left parahippocampal gyrus | 4.94 | 0.022 | 0.013 |
7 | 5 | 44 | 18 | 62 | Right medial frontal gyrus | 4.93 | 0.022 | 0.397 |
8 | 29 | 16 | −5 | 1180 | Right insula | 4.85 | 0.022 | 0.001 |
9 | −40 | −31 | 15 | 90 | Left superior temporal gyrus | 4.11 | 0.023 | 0.306 |
10 | 35 | −41 | −23 | 90 | Right cerebellar culmen | 4.07 | 0.023 | 0.306 |
11 | −45 | −8 | 5 | 53 | Left insula | 3.80 | 0.025 | 0.436 |
12 | 23 | −38 | −12 | 75 | Right cerebellar culmen | 3.79 | 0.025 | 0.351 |
13 | 3 | −18 | 12 | 200 | Right thalamus | 3.55 | 0.028 | 0.133 |
14 | 19 | −53 | 6 | 74 | Right posterior cingulate | 3.51 | 0.028 | 0.354 |
VBM, voxel-based morphometry; ADNI, Alzheimer’s Disease Neuroimaging Initiative; MCI, mild cognitive impairment; AD, Alzheimer’s disease; FDR, false discovery rate.