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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Biochim Biophys Acta. 2018 Apr 19;1864(7):2438–2447. doi: 10.1016/j.bbadis.2018.04.010

Figure 4. Blockade of IL-7Rα reduces TNF-α levels and increases claudin-1 and AQP5 amounts in the SMGs.

Figure 4

Anti-IL-7Rα antibody or control IgG was i.p.-administered to 10-week-old female NOD mice 3 times weekly for 3 weeks. (A) Immunohistochemical staining of TNF-α and claudin-1 protein in SMG sections (scale bar = 50μm). Bar graph shows the percentage of positively stained areas in the sections. (B) Immunofluorescence staining of AQP5 protein in SMG sections (scale bar = 100μm). Bar graph shows the fluorescence intensity of AQP5 staining. Data are representative or the average of analyses of 7 mice each group.