Table 3.
The enriched GO biological process terms that are related to the genes in each of the LSM clusters for each of the 9 subjects.
| Subject | The most enriched gene ontology (GO) BP terms |
|---|---|
| 1 | (i) negative regulation of cell growth, (ii) translation, (iii) adaptive immune response, (iv) negative regulation of epithelial cell proliferation, (v) translational elongation, (vi) inflammatory response, (vii) sphingolipid metabolic process |
| 5 | (i) positive regulation of cell motion, (ii) negative regulation of cell growth, (iii) regulation of transcription, (iv) cellular macromolecule catabolic process, (v) DNA replication, (vi) protein modification by small protein conjugation |
| 6 | (i) protein amino acid phosphorylation, (ii) cholesterol metabolic process (iii) response to virus (iv) innate immune response (v) negative regulation of transcription, (vi) innate immune response (vii) DNA metabolic process, (viii) positive regulation of immune response, (ix) translational elongation (x) mRNA metabolic process |
| 7 | (i) phosphate metabolic process, (ii) hexose metabolic process, (iii) carboxylic acid catabolic process (iv) defense response (v) monosaccharide metabolic process (vi) translation |
| 8 | (i) chromatin modification (ii) positive regulation of I-kappaB kinase/NF-kappaB cascade (iii) cellular amide metabolic process (iv) proteolysis (v) positive regulation of macromolecule biosynthetic process |
| 10 | (i) response to wounding (ii) chromatin modification (iii) cofactor metabolic process (iv) positive regulation of I-kappaB kinase/NF-kappaB cascade (v) icosanoid metabolic process |
| 12 | (i) translational elongation (ii) nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process (iii) cellular carbohydrate catabolic process (iv) small GTPase mediated signal transduction (v) inflammatory response (vi) proteolysis |
| 13 | (i) membrane organization (ii) translational elongation (iii) regulation of protein amino acid phosphorylation (iv) inflammatory response (v) histone acetylation |
| 15 | (i) regulation of transcription (ii) cellular protein complex assembly (iii) nicotinamide metabolic process (iv) Wnt receptor signaling pathway (v) innate immune response (vi) steroid metabolic process |