Table 3.
Difference of histogram parameters between benign and malignant lesions
| Parameters | Benign group | Malignant group | t-value | p-value |
|---|---|---|---|---|
| ADCmean | 1.486 ± 0.245 | 1.140 ± 0.188 | 7.696 | 0.000 |
| SD | 0.161 ± 0.056 | 0.197 ± 0.077 | −2.665 | 0.009 |
| Skewness | 0.447 ± 0.612 | 0.635 ± 0.630 | −3.918 | 0.084 |
| Kurtosis | 3.276 ± 1.144 | 4.064 ± 1.361 | −3.056 | 0.003 |
| ADCmin | 1.046 ± 0.295 | 0.690 ± 0.207 | 6.790 | 0.000 |
| ADCmax | 1.849 ± 0.255 | 1.752 ± 0.305 | 1.682 | 0.096 |
| ADC10 | 1.279 ± 0.251 | 0.903 ± 0.137 | 9.033 | 0.000 |
| ADC20 | 1.351 ± 0.251 | 0.982 ± 0.158 | 8.548 | 0.000 |
| ADC25 | 1.384 ± 0.251 | 1.008 ± 0.166 | 8.595 | 0.000 |
| ADC30 | 1.409 ± 0.253 | 1.030 ± 0.173 | 8.503 | 0.000 |
| ADC40 | 1.455 ± 0.253 | 1.071 ± 0.178 | 8.517 | 0.000 |
| ADC50 | 1.495 ± 0.258 | 1.113 ± 0.186 | 8.263 | 0.000 |
| ADC60 | 1.535 ± 0.259 | 1.167 ± 0.207 | 7.646 | 0.000 |
| ADC70 | 1.574 ± 0.258 | 1.223 ± 0.227 | 7.033 | 0.000 |
| ADC75 | 1.594 ± 0.256 | 1.255 ± 0.237 | 6.694 | 0.000 |
| ADC80 | 1.622 ± 0.254 | 1.297 ± 0.250 | 6.295 | 0.000 |
| ADC90 | 1.682 ± 0.244 | 1.403 ± 0.260 | 5.388 | 0.000 |
ADC, apparent diffusion coefficient; ADCn, nth percentile value of cumulative ADC histogram; SD, standard deviation. Except t-value and p-value, data are reported as mean ± SD. The unit for ADC value is ×10–3 mm2 s–1.