Table 5.
Patient characteristics and imaging findings of 23 patients with cystic mesothelioma
| Variables | n (%) n = 23 | Male (n = 10) | Female (n = 13) | p value |
|---|---|---|---|---|
| Age | 23 | 49.9 ± 15.1 years (30–70 years) | 50.2 ± 13 years (30–67 years) | 0.956 |
| Distribution: | ||||
| Diffuse | 7 (30.4) | 2 | 5 | 0.634 |
| Localized | 16 (69.5) | 8 | 8 | |
| rPCI | 23 | 20 ± 9 | 11 ± 10 | 0.046 |
| Size of lesion | 23 | 21 ± 8.4 cm (15–43 cm) | 14.2 ± 6.7 cm (4–28 cm) | 0.06 |
| Morphology of the lesions: | ||||
| Multiloculated cystic lesion | 21 (91.3) | 10 | 11 | 0.545 |
| No perceptible loculations | 2 (8.6) | 0 | 2 | |
| Enhancing septae | 4 (17.4) | 2 | 2 | 0.632 |
| Size of the locule | 21 | 6 ± 3.6 cm | 4.5 ± 6 cm | 0.437 |
| Locations of the lesions within the peritoneal cavity: | ||||
| Sub phrenic space | 4 (17.4) | 3 | 1 | 0.200 |
| Lesser omentum/lesser sac | 5 (21.7) | 4 | 1 | 0.089 |
| Porta hepatis | 3 (13) | 2 | 1 | 0.398 |
| Greater omentum | 13 (56.6) | 8 | 5 | 0.195 |
| Small bowel mesentery | 12 (52.2) | 8 | 4 | 0.026 |
| Root of mesentry | 1 (4.3) | 0 | 1 | 0.565 |
| Small Bowel | 5 (21.7) | 4 | 1 | 0.089 |
| Pelvis | 21 91.3) | 9 | 12 | 0.189 |
| Pelvic side wall | 1 (4.3) | 0 | 1 | 0.565 |
| Hydronephrosis | 1 (4.3) | 1 | 0 | 0.435 |
| Paracolic gutters | 13 (56.5) | 6 | 7 | 0.955 |
| Other findings: | ||||
| Ascites | 6 (26) | 4 | 2 | 0.197 |
| Peritoneal thickening | 4 (17.4) | 2 | 2 | 0.596 |
| Ovarian/adnexal lesions | 4 | - | 4 | |
| Epiphrenic nodes | 2 (8.6) | 1 | 1 | 0.692 |
| Pleural plaques | 1 (4.3) | 1 | 0 | |
| Intrathoracic disease | 0 | 0 | 0 | |
| Treatment and outcome: | ||||
| Surgical PCI | 10 | 20 ± 11 | 9 ± 5 | 0.045 |
| Surgery: | ||||
| CC + HIPEC | 21 (91.3) | 9 | 12 | 0.355 |
| MTD | 1 (4.3) | 0 | 1 | |
| EPIC | 4 (17.4) | 1 | 3 | |
| Recurrence | 2 (8.6) | 2 | 0 | 0.178 |
| Time of recurrence | 2 | 5 months, 18 months | - | |
| Survival: | 23 | 49.7 ± 26.4 months | 51 ± 23 months | 0.895 |
| Alive | 22 | 10 | 12 | 0.565 |
| Dead | 1 | 0 | 1 |
CC, complete cytoreduction; EPIC, early post-operative intraperitoneal chemotherapy; HIPEC, intraoperative hyperthermic intraperitoneal chemotherapy; MTD, major tumour debulking; rPCI, radiologicalperitoneal cancer index.