Table 4.
Univariate analysis of the risk factors of HI with different margin definition
| |
The expanded margin of peri-hippocampus |
|||||
|---|---|---|---|---|---|---|
| 5 mm | 10 mm | 20 mm | ||||
| OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |
| Age | ||||||
| ≥60 vs <60 | 0.99 (0.93–1.06) | 0.83 | 0.99 (0.95–1.04) | 0.78 | 0.99 (0.95–1.03) | 0.73 |
| Sex | ||||||
| Male vs female | 0.71 (0.16–3.27) | 0.67 | 0.41 (0.12–1.367) | 0.14 | 0.68 (0.2633–1.76) | 0.42 |
| Extracranial tumour | ||||||
| Active vs stable | 3.75 (0.27–51.37) | 0.32 | 0.4 (0.03–6.18) | 0.51 | 0.54 (0.96–2.99) | 0.48 |
| Extracranial metastases | ||||||
| No vs yes | 1.95 (0.36–10.89) | 0.43 | 0.87 (0.28–2.68) | 0.81 | 0.65 (0.25–1.67) | 0.37 |
| BM status | ||||||
| Synchronous vs metachronous | 0.35 (0..04–2.98) | 0.34 | 0.38 (0.81–1.75) | 0.21 | 0.76 (0.26–2.19) | 0.61 |
| Number of BM | ||||||
| Continuous variable | 1.08 (1.03–1.12) | 0.002 | 1.08 (1.03–1.13) | 0.001 | 1.08 (1.03–1.12) | 0.001 |
| >3 vs 1–3 | 3.38 (0.73–15.52) | 0.12 | 4.28 (1.34–13.60) | 0.14 | 3.00 (1.16–7.76) | 0.24 |
| >4 vs 1–4 | 2.90 (0.63–13.43) | 0.29 | 3.49 (1.11–10.93) | 0.15 | 3.04 (1.15–8.04) | 0.10 |
| >5 vs 1–5 | 3.81 (0.82–17.77) | 0.09 | 4.68 (1.48–14.79) | 0.01 | 4.13 (1.54–11.08) | 0.01 |
| >6 vs 1–6 | 4.91 (1.05–23.01) | 0.04 | 4.31 (1.31–14.13) | 0.02 | 3.21 (1.12–9.19) | 0.03 |
| Primary tumour | 0.83 (0.22–3.51) | 0.78 | 0.88 (0.34–2.31) | 0.80 | 0.61 (0.23–1.59) | 0.31 |
BM, brain metastase.