Table 1.

Participant characteristics

	Healthy controls	RRMS	SPMS
n	38	43	28
Mean age, years ± SD (range)	39.1 ± 11.9 (23–63)	42.5 ± 10.0 (25–64)	53.0 ± 8.1 (36–65)
Gender male/female	17/21	14/29	9/19
Median EDSS (range)	NA	2 (1.0-7.0)	6.5 (4.0–8.5)
Disease duration, years ± SD	NA	11.7 ± 8.1	21.9 ± 10.4
Mean MTR in whole NAWM ± SD	39.7 ± 0.8	38.9 ± 1.5	38.4 ± 1.9
Mean number of bands extracted ± SD	44.0 ± 3.2	42.7 ± 3.2	41.1 ± 3.8
Mean brain parenchymal fraction ± SD	0.82 ± 0.02	0.80 ± 0.02	0.80 ± 0.03

EDSS = Expanded Disability Status Scale; NA = not available.