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Selective histone deacetylase 6 (HDAC6) inhibitor, ACY-1215, shows enhanced efficacy in suppressing cyst growth in polycystic kidney (PCK) rats. A and B: ACY-1215 decreases hepatic (A) and renal (B) cystic and fibrotic areas to a higher extent than panobinostat, ACY-241 and ACY-748. Data are expressed as means ± SD. ∗P < 0.05.
