. Author manuscript; available in PMC: 2018 May 22.

Published in final edited form as: Respir Med. 2014 Dec 18;109(4):463–474. doi: 10.1016/j.rmed.2014.12.002

Table 1.

Subject demographics and baseline pulmonary function.

	Healthy	CF
n	16	14
Gender male (%)	10 (63)	12 (86)
Age (years)	24 ± 6	22 ± 8
Height (cm)	168 ± 8	166 ± 17
Weight (kg)	70 ± 12	62 ±12
BMI (kg/m²)	24 ± 3	22 ±2
BSA (m²)	1.8 ± 0.2	1.7 ± 0.3
VO_2PEAK (% predicted)	106 ± 23	78 ± 18^*
Exercise (hr/wk)	5.5 ± 4.5	6.8 ± 4.5
Pulmonary function
FVC (L)	4.6 ± 0.9	4.0 ± 1.2
FVC (% predicted)	100 ± 9	96 ± 30
FEV₁ (L)	3.8 ± 0.9	2.9 ± 1.1^*
FEV₁ (% predicted)	99 ± 12	83 ± 28
FEV₁/FVC (%)	84 ± 4	73 ± 10^*
FEF_25–75 (L/sec)	4.0 ± 1.2	2.4 ± 1.4^*
FEF_25–75 (% predicted)	96 ± 26	60 ± 30^*

BMI = body mass index; BSA = body surface area; VO_2peak= maximal oxygen consumption. FVC = forced vital capacity; FEV₁ = forced expiratory volume after one second of FVC; FEF_25–75 = forced expiratory flow at 25–75% of FVC. Data presented are mean ± SD

p < 0.0025 vs. healthy.