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. Author manuscript; available in PMC: 2019 Mar 16.
Published in final edited form as: Org Lett. 2018 Mar 5;20(6):1621–1625. doi: 10.1021/acs.orglett.8b00364

Scheme 2. Peptide optimization studiesa.

Scheme 2

aReactions were performed on a 0.05 mmol scale and were quenched by exposure to air. Conversions, diastereomeric ratios, and enantiomeric excesses were determined by CSP-HPLC (254 nm, uncorrected). Ar = 4-CF3Ph.