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Potency estimates of the antagonism of ACh-stimulated IP1 accumulation by GSK1034702 or TBPB in CHO Flp-In cells expressing the human M1 mAChR
Data are the means ± S.E.M. of three independent experiments performed in duplicate.
| Parameter | GSK1034702 | TBPB | n |
|---|---|---|---|
| pA2 | 6.2 ± 0.2 | 7.0 ± 0.1 | 3 |
| Schild slope | 1.1 ± 0.1 | 1.2 ± 0.1 | 3 |
