TABLE 5.
Negative logarithms of the equilibrium dissociation constant (pKi) of GSK1034702 binding to M1–M5 mAChRs
Data are calculated from the means ± S.E.M. of three independent experiments performed in duplicate.
mAChR subtype | pKi | n |
---|---|---|
M1 | 6.0 ± 0.1 | 3 |
M2 | 5.4 ± 0.1 | 3 |
M3 | n.d. | 3 |
M4 | 5.7 ± 0.1 | 3 |
M5 | 5.2 ± 0.1 | 3 |
n.d., not determined.