Table 3. Results on epidemiological criteria regarding the primary and secondary outcomes.

	Outcome	p<0.001	Adequate sample size	Heterogeneity not a problem	PrI consistent	Egger’s test NS	Criteria met
Intraoral appliance versus placebo appliance
A	AHIcon	Yes	Yes	Yes	Yes	Yes	Yes
B	ESS	No	No	No	No	Yes	No
C	Min satur	No	No	Yes	No	–	No
Intraoral appliance versus no appliance
D	AHIcon	Yes	No	–	–	–	No
E	AHIbin	No	No	–	–	–	No
F	ESS	No	No	–	–	–	No
Intraoral appliance1 versus intraoral appliance2
G	AHI	No	No	–	–	–	No
H	ESS	Yes	No	–	–	–	No

PrI, predictive intervals; NS, not significant; AHI, apnea hypopnea index; Min Satur, minimum oxygen saturation; ESS, Epworth Sleepiness Scale; con, continuous;

bin, binary; intraoral appliance₁, intraoral appliance with 4 mm opening; intraoral appliance₂, intraoral appliance with 14 mm opening