Table 1. Response assessment (n = 9).
Dose of F50067 (mg/kg) | Single agent | Overall | F50067 Len-Dex | Overall | ||||
---|---|---|---|---|---|---|---|---|
0.03 | 0.1 | 0.3 | 1 | 0.03 | 0.1 | |||
N total of patients | 1 | 4 | 3 | 2 | 10 | 1 | 3 | 4 |
N response assessed* | 0 | 2 | 3 | 1 | 6 | 1 | 2 | 3 |
Partial response (PR) | - | 0 | 0 | 0 | 0 | 1 | 1 | 2 (66.7%) |
Stable disease (SD) | - | 0 | 1 | 1 | 2 (33.3%) | 0 | 0 | 0 |
ORR (≥PR) | - | 0 | 0 | 0 | 0 | 1 | 1 | 2 (66.7%) |
CBR (≥MR) | - | 0 | 0 | 0 | 0 | 1 | 1 | 2 (66.7%) |
Objective response (≥SD) | - | 0 | 1 | 1 | 2 (33.3%) | 1 | 1 | 2 (66.7%) |
*Patients not evaluable for response: no response at cycle 1, not evaluable at cycle 1 or not eligible