Figure 2. EMT factors are exclusively restricted to vascular proliferations in human astrocytomas.

Double immunohistochemistry for GFAP (red) and (A, B) SLUG (brown) as well as (C, D) TWIST (brown) indicating that all cells expressing the EMT transcriptions factors are GFAP-negative and are located within abnormal vascular complexes. (insets: higher magnifications; scale bar in A, C = 200μm and in B, D = 100μm).