Table 1. Epidemiological and clinical features of the cohort of patients with benign and malignant melanocytic lesions according to cofilin-1 immunocontent.
| Characteristics | Cofilin-1 Immunocontent | |
|---|---|---|
| Low (< 0.08 A.U.) | High (> 0.08 A.U.) | |
| Cohort, n=42 | 57.1 % | 42.9 % |
| Age, years | 58.6 ± 21.3 | 69.6 ± 16.6 |
| Sex | ||
| Men, n=22 | 59.1 % | 40.9 % |
| Women, n=18 | 50 % | 50 % |
| Undetermined, n=2 | 100 % | 0 % |
| Histological Type | ||
| Nevus, n=9 | 100 % | 0 % |
| MIS, n=8 | 87.5 % | 12.5 % |
| MM | ||
| SSM, n=5 | 80 % | 20 % |
| LMM, n=1 | 0 % | 100 % |
| NMM, n=10 | 30 % | 70 % |
| Undetermined MM, n=9 | 11.1 % | 88.9 % |
| Tumor Stage (TNM) | ||
| 0, n=8 | 87.5 % | 12.5 % |
| IA, n=4 | 50 % | 50 % |
| IB, n=4 | 50 % | 50 % |
| IIB, n=1 | 100 % | 0 % |
| III, n=2 | 50 % | 50 % |
| IV, n=9 | 22.2 % | 77.8 % |
| Undetermined, n=5 | 0 % | 100 % |
| Metastasis | ||
| No, n=17 | 70.6 % | 29.4 % |
| Yes, n=11 | 18.2 % | 81.8 % |
| Mitosis/Field | ||
| < 1, n=10 | 60 % | 40 % |
| 1-5, n=13 | 15.4 % | 84.6 % |
| > 5, n=1 | 0 % | 100 % |
| Breslow Index | ||
| < 2 mm, n=10 | 50 % | 50 % |
| > 2 mm, n=15 | 20 % | 80 % |
Metastasis includes lymph nodes and distant metastases. Abbreviations: LMM, Lentigo maligna melanoma; MIS, Melanoma in situ; MM, Malignant melanoma; SSM, Superficial spreading melanoma; NMM, Nodular malignant melanoma.