Table 3. Genotypes of selected SNPs and OSCC risk in different models.
| Positive SNPs | Calculation models | Case (%) (n = 444) | Control (%) (n = 984) | Adjusted OR a(95%CI) | pa |
|---|---|---|---|---|---|
| rs217727 | CC | 186 (41.89) | 488 (49.59) | 1 | |
| CT | 194 (43.69) | 423 (42.99) | 1.24 (0.97-1.58) | 0.080 | |
| TT | 51 (11.49) | 73 (7.42) | 1.89 (1.27-2.82) | 0.002 | |
| Dominant | 1.34 (1.06-1.68) | 0.013 | |||
| Recessive | 1.70 (1.16-2.49) | 0.006 | |||
| Additive | 1.32 (1.11-1.58) | 0.002 | |||
| rs2839701 | CC | 205 (46.17) | 507 (51.52) | 1 | |
| CG | 188 (42.34) | 402 (40.85) | 1.15 (0.91-1.46) | 0.248 | |
| GG | 51 (11.49) | 75 (7.62) | 1.64 (1.10-2.43) | 0.014 | |
| Dominant | 1.23 (0.98-1.54) | 0.075 | |||
| Recessive | 1.53 (1.05-2.24) | 0.027 | |||
| Additive | 1.23 (1.04-1.46) | 0.019 |
aORs and 95% CIs were calculated after adjusting for age, sex, smoking and drinking status by using logistic regression analyses.