Table 2. DII distribution according to confounders among controls.

Controls	DII quartiles (%)
	1 (−4.31– −1.00)	2 (−1.00–0.11)	3 (0.11–0.58)	4 (0.58–2.02)	P value
Sex					<0.001
Male	538 (21.8)	607 (24.6)	628 (25.5)	693 (28.1)
Female	233 (37.9)	163 (26.5)	142 (23.1)	77 (12.5)
Age					<0.001
<40	30 (17.5)	34 (19.9)	37 (21.6)	70 (40.9)
40–49	54 (19.6)	57 (20.7)	84 (30.4)	81 (29.4)
50–59	180 (19.9)	221 (24.4)	262 (28.9)	244 (26.9)
60–69	317 (27.7)	295 (25.8)	261 (22.8)	271 (23.7)
70-	190 (32.6)	163 (28.0)	126 (21.6)	104 (17.8)
Smoking					<0.001
Non	378 (33.3)	279 (24.6)	254 (22.4)	224 (19.7)
Low-Modarate	114 (20.80)	141 (25.7)	147 (26.8)	146 (26.6)
High-Moderate	137 (21.5)	169 (26.6)	163 (25.6)	167 (26.3)
Heavy	140 (19.2)	172 (23.6)	197 (27.0)	221 (30.3)
Unknown	2 (6.3)	9 (28.1)	9 (28.1)	12 (37.5)
Alcohol consumption					0.02
Non	269 (26.4)	259 (25.4)	244 (24.0)	247 (24.2)
Moderate	219 (25.8)	196 (23.1)	207 (24.4)	226 (26.7)
1-2 go×5/week	191 (26.9)	185 (26.0)	171 (24.1)	164 (23.1)
>2 go×5/week	83 (17.8)	119 (25.5)	137 (29.3)	128 (27.4)
Unknown	9 (25.0)	11 (30.6)	11 (30.6)	5 (13.9)
Flushing phenotype					0.19
Yes	383 (24.6)	383(24.6)	377 (24.2)	412 (26.5)
No	363 (25.0)	368 (25.3)	378 (26.0)	346 (23.8)
Unknown	25 (35.2)	19 (26.8)	15 (21.1)	12 (16.9)
Teeth					0.62
0	28 (23.1)	33 (27.3)	30 (24.8)	30 (24.8)
1-8	93 (24.9)	98 (26.2)	81 (21.7)	102 (27.3)
9-20	218 (24.8)	208 (23.7)	231 (26.3)	222 (25.3)
≥21	424 (25.3)	427 (25.5)	419 (25.0)	403 (24.1)
Unknown	8 (23.5)	4 (11.8)	9 (26.5)	13 (38.2)
Occupation group					<0.001
Blue collar	143 (17.0)	191 (22.7)	230 (27.4)	277 (32.9)
White collar	198 (21.6)	241 (26.3)	234 (25.5)	244 (26.6)
Other	411 (32.3)	323 (25.4)	295 (23.2)	243 (19.1)
Unknown	19 (37.3)	15 (29.4)	11 (21.6)	6 (11.8)