Table 3.
Antidiabetic effect of Juniperus fruit ethanol extracts in STZ-diabetic rats
| Group |
Dose
(mg/kg) |
Blood Glucose Concentration (mg/dL) Standart Error of the Mean (Inhibition %)
|
|||||
|---|---|---|---|---|---|---|---|
| Initial | ½ h | 1 h | 2 h | 4 h | 6 h | ||
| Control | - | 372.8 ± 24.0 | 376.3 ± 5.4 | 382.2 ± 4.2 | 350.7 ± 7.1 | 311.3 ± 6.1 | 313.2 ± 3.9 |
| Glipizide | 10 | 372.0 ± 29.5 | 338.4 ± 4.0*** (10.1 %) |
342.1 ± 4.9*** (10.5 %) |
323.1 ± 10.7** (7.9 %) |
307.4 ± 10.8 (1.3 %) |
309.4 ± 10.7 (1.2 %) |
| Jf | 500 | 376.6 ± 39.7 | 371.5± 19.9 (1.3 %) |
341.3 ± 7.6*** (10.7 %) |
325.5 ± 22.7* (7.2 %) |
277.6 ± 4.1 (10.8 %) |
306.0 ± 19.6 (2.3 %) |
| 1000 | 380.8 ± 28.9 | 393.0 ± 17.2 | 393.8 ± 12.2 | 365.4 ± 14.6 | 306.0 ± 21.8 (1.7 %) |
287.3 ± 12.6 (8.3 %) |
|
| Js | 500 | 382.8 ± 35.5 | 386.6 ± 20.6 | 413.2 ± 26.7 | 339.0 ± 20.97 (3.4 %) |
311.2 ± 35.9 | 335.6 ± 46.5 |
| 1000 | 372.1 ± 22.2 | 397.0 ± 25.3 | 406.8 ± 24.5 | 348.1 ± 17.4 (0.7 %) |
293.7 ± 24.3 (5.7 %) |
283.7 ± 21.2 (9.4 %) |
|
Jf: Juniperus foetidissima, Js: J. sabina,
*
: p<0.05,
**
: p<0.01,
***
: p<0.001